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Masahiko Nakano Selected Research

PQQ Cofactor (Pyrroloquinoline Quinone)

12/2012Effect of pyrroloquinoline quinone on neuropathic pain following chronic constriction injury of the sciatic nerve in rats.
11/2012Pyrroloquinoline quinone, a novel protein tyrosine phosphatase 1B inhibitor, activates insulin signaling in C2C12 myotubes and improves impaired glucose tolerance in diabetic KK-A(y) mice.
7/2008Pyrroloquinoline quinone prevents oxidative stress-induced neuronal death probably through changes in oxidative status of DJ-1.

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Masahiko Nakano Research Topics

Disease

3Hyperglycemia
07/2009 - 03/2004
3Type 1 Diabetes Mellitus (Autoimmune Diabetes)
10/2005 - 03/2004
2Hypoglycemia (Reactive Hypoglycemia)
02/2005 - 03/2004
1Enteritis
04/2021
1Peritonitis
04/2021
1Muscular Atrophy (Muscle Atrophy)
12/2012
1Hyperalgesia
12/2012
1Neuralgia (Stump Neuralgia)
12/2012
1Type 2 Diabetes Mellitus (MODY)
11/2012
1Insulin Resistance
11/2012
1Glucose Intolerance
11/2012
1Stomach Neoplasms (Stomach Cancer)
01/2011
1Fistula
01/2010
1Crohn Disease (Crohn's Disease)
01/2010
1Colorectal Neoplasms (Colorectal Cancer)
01/2010
1Stroke (Strokes)
07/2008
1Hyperoxia
01/2008
1Overweight
09/2004
1Lymphopenia (Lymphocytopenia)
03/2004

Drug/Important Bio-Agent (IBA)

3PQQ Cofactor (Pyrroloquinoline Quinone)IBA
12/2012 - 07/2008
3Insulin (Novolin)FDA Link
11/2012 - 03/2004
2Streptozocin (Streptozotocin)FDA Link
04/2007 - 03/2004
1Therapeutic UsesIBA
12/2012
1Tyrosine (L-Tyrosine)FDA Link
11/2012
1Insulin ReceptorIBA
11/2012
1Non-Receptor Type 1 Protein Tyrosine PhosphataseIBA
11/2012
1Bevacizumab (Avastin)FDA Link
01/2010
1Infliximab (Remicade)FDA Link
01/2010
1Adenosine (Adenocard)FDA LinkGeneric
07/2009
1InterferonsIBA
07/2009
1AntioxidantsIBA
07/2008
1Vitamin EFDA LinkGeneric
01/2008
1coenzyme Q10 (CoQ10)IBA
01/2008
1C-PeptideIBA
03/2004

Therapy/Procedure

4Transplantation
07/2009 - 03/2004
2Oral Administration
12/2012 - 11/2012
2Therapeutics
01/2010 - 01/2010
1Radiotherapy
04/2021
1Hysterectomy
04/2021
1Gastroenterostomy
01/2011
1Gastrectomy
01/2011
1Immunotherapy
02/2005
1Islets of Langerhans Transplantation
02/2005